Dose-Response Relationship of Crude Cobra Venom in the Dog
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چکیده
منابع مشابه
Cobra Venom in Therapeutics
During the past eight years the senior author has been engaged in testing the pharmacological action and therapeutic properties of Indian snake venoms. Chopra and Chowhan (1932 and 1935) showed that the efficacy of the cobra and other snake venoms in relieving the pain of malignant growths and of neuritis and neuralgias was probably due to the presence of such active principles as neurotoxin. The
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Interest in the alternate or C3 shunt complement pathway has recently been generated by a number of reports (1-5). Its presence in invertebrates points to a primitive phylogenetic appearance (6). The C3 shunt can be triggered by high molecular weight polysaccharides in a manner reminiscent of the properdin system (7). Once activated by cobra venom, erythrocytes and other cells can be lysed in t...
متن کاملCobra Venom Factor and Ketoprofen Abolish the Antitumor Effect of Nerve Growth Factor from Cobra Venom
We showed recently that nerve growth factor (NGF) from cobra venom inhibited the growth of Ehrlich ascites carcinoma (EAC) inoculated subcutaneously in mice. Here, we studied the influence of anti-complementary cobra venom factor (CVF) and the non-steroidal anti-inflammatory drug ketoprofen on the antitumor NGF effect, as well as on NGF-induced changes in EAC histological patterns, the activity...
متن کاملThe Basic Proteins of Cobra Venom
Cobra venoms contain heat stable, basic, proteins that inhibit iodide accumulation by thyroid slices. Activity is not related to the content of phospholipase A or various other enzymatic activities. These proteins are present only in Elapid venoms and not in snakes of the Crotalidae or Viperidae families. Two such basic proteins, named cobramines A and B, have been purified from the crude venom...
متن کاملCHARACTERIZATION OF AN ANTICOAGULANT AGENT IN THE VENOM OF IRANIAN COBRA (NAJA NAJA OXIANA).
Snake venoms contain a rich variety of factors which affect blood coagulation. There have been few reports on the anticoagulant activity of the venom of different cobras, but no such observations have been made on the Iranian cobra, although a procoagulant factor has been described. In this study an anticoagulant factor has been purified from the venom of Naja naja oxiana using gel filtrat...
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ژورنال
عنوان ژورنال: Military Medicine
سال: 1968
ISSN: 0026-4075,1930-613X
DOI: 10.1093/milmed/133.4.295